Breast tumor tissues have increased OPN transcript levels but comparable Merlin transcript levels relative to normal breast tissues. A, the overall levels of Merlin are not significantly reduced (p = 0.82) in tumor tissues relative to normal breast tissues. B and C, there is no appreciable change in the levels of Merlin across the grade (p = 0.6) of the breast tumor tissues and the disease stage (p = 0.15). D, the transcript levels of OPN are significantly increased (^, p = 0.0028) in breast tumor tissues relative to normal breast tissues. E and F, the transcript levels of OPN are notably increased with the advance in the grade of the breast tumor (^, p = 0.04) and disease stage (^, p = 0.01). Error bars in all panels indicate S.D.