Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Substitutions of Eco β′Arg-933 (Tth Arg-1239) abolish inhibition by Tgt. A, polar contacts between Tgt (purple sticks) and amino acids (orange and gray sticks) in the model of Tgt/EC (shown in Fig. 4; the color scheme is preserved). B and C, inhibition of abortive transcription on the T7A1 promoter by Tgt. Formation of the radiolabeled ApUpC RNA was followed as a function of Tgt concentration (from 0 to 32 μm) with the wild-type or altered Eco RNAPs. The key is shown in the figure.
