Table 2.
Comparison between experimental data and model simulations for growth on eleven different carbon sources.
| Carbon Source | Experimental | Computational | Comments |
|---|---|---|---|
| Gluconate | Yes (0.27) | Yes | |
| Without citrate: 0.27 | |||
| With citrate: 0.28 | |||
| Glucose | Yes (0.29) | Yes | |
| Without citrate: 0.28 | |||
| With citrate: 0.28 | |||
| Glycerol | No | Yes | Model suggests glycerol can enter central metabolism indirectly through fatty acid biosynthesis and degradation pathways, thereby permitting slow growth |
| Acetate | Yes (0.14) | Yes | |
| Citrate | Yes (0.086) | Yes | |
| Lactate | Yes (0.12) | Yes | |
| Xylose | Yes (0.20) | Yes | |
| Ribose | Yes (0.17) | Yes | |
| Galactose | Yes (0.16) | Yes | |
| Maltose | Yes (0.27) | Yes | |
| Arabinose | Yes (0.28) | Yes |
Values in parentheses in the Experimental column are the measured growth rates performed as part of this study. Values in parentheses in the Computational column indicate model-predicted growth rates in BCS defined media with or without citrate and with glucose or gluconate as the principal carbon source.