Table 2.
Potential horizontal gene transfers identified
| Score | PAH-LLAP | PAH-Legionellales | Legionellales-Chlamydiales | PAH/LLAP-Rickettsiales | PAH/LLAP-Others | Gene product | COG accession | COG group |
|---|---|---|---|---|---|---|---|---|
| 0 | 101 | Hypothetical protein | ||||||
| 158 | Choloylglycine hydrolase | COG3049 | M | |||||
| 191 | 191 PAH-Rickettsiales | Acetyltransferase | COG0454 | KR | ||||
| 192 | 192 PAH-Wolbachia | Aminoglycoside phosphotransferase family protein | COG3173 | R | ||||
| 473 | putative phosphotransferase | COG2334 | R | |||||
| 475 | Hypothetical protein | COG0500 | QR | |||||
| 492 | Toluene efflux pump outer membrane protein | COG1538 | MU | |||||
| 1 | 96 | Conserved hypothetical protein | COG0599 | S | ||||
| 127 | ABC-type multidrug transporter, permease | COG0842 | V | |||||
| 128 | ABC-type multidrug transporter, ATP-binding protein | COG1131 | V | |||||
| 129 | HlyD family secretion protein | COG0845 | M | |||||
| 243 LLAP-Rickettsia | Beta-lactamase | COG2602 | V | |||||
| 246 | Acetyltransferase, GNAT family | COG0454 | KR | |||||
| 247 | Hypothetical protein | COG2132 | Q | |||||
| 282 | Conserved hypothetical protein | COG4804 | S | |||||
| 387 | 387 PAH-Legionellales-Orientia | Hypothetical protein | COG0500 | QR | ||||
| 2 | 11 | Succinylarginine dihydrolase | COG3724 | E | ||||
| 86 | Metallo-beta-lactamase family protein | COG1234 | R | |||||
| 166 | Multidrug resistance protein | COG0477 | GEPR | |||||
| 207 | 207 LLAP-Naegleria | 7-dehydrocholesterol reductase | COG2020 | O | ||||
| 301 | Acyl-CoA dehydrogenase | COG1960 | I | |||||
| 388 LLAP-Rickettsia | Aminoglycoside N(6')-acetyltransferase | COG1670 | J | |||||
| 400* | Putative transcriptional regulator | COG0583 | K | |||||
| 421 | Putative outer membrane efflux protein | COG1538 | MU | |||||
| 458 Chlamydiales-Eukaryotes | Alpha keto acid dehydrogenase complex E1 component alpha subunit | COG1071 | C | |||||
| 474 | DNA protection during starvation protein | COG0783 | P | |||||
| 3 | 90 | Multidrug resistance protein B homolog | COG0477 | GEPR | ||||
| 130 | Solvent efflux pump outer membrane protein | COG1538 | MU | |||||
| 134 Chlamydiales-Ehrlichia/Wolbachia | Proton/sodium-glutamate symport protein | COG1301 | C | |||||
| 208 LLAP-A.asiaticus | PEBP family protein | COG1881 | R | |||||
| 211 PAH-Rickettsia | Putative 6-pyruvoyl tetrahydrobiopterin synthase | COG0720 | H | |||||
| 240 LLAP-Eukaryotes | Hypothetical protein | COG1092 | R | |||||
| 263 | 263 LLAP-Rickettsia | DNA protection during starvation protein 2 | COG0783 | P | ||||
| 390 Legionellales-Rickettsiales | ABC-type transporter, permease and ATPase subunit | COG1132 | V | |||||
| 413 | Cation-transporting ATPase | COG2217 | P | |||||
| 422* | Inner membrane transport permease YbhR | COG0842 | V | |||||
| 466* | Methylisocitrate lyase | COG2513 | G |
* clustering with Legionella pneumophila only, PAH = Parachlamydia acanthamoebae, LLAP = Legionella drancourtii
This table presents the classification by score and ID numbers of the L. drancourtii and P. acanthamoebae orthologues that exhibit a phylogenetic reconstruction suggesting horizontal gene transfer events. The gene product annotation, COG accession number and COG group are indicated for each gene.