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. 2011 Nov 18;6(11):e28039. doi: 10.1371/journal.pone.0028039

Figure 3. Increased germ cell apoptosis in Ctnnb1 FΔ mice testes.

Figure 3

(A) TUNEL analysis of apoptotic germ cells in control (panel a) and Ctnnb1 FΔ (panels b-d) mice testes sections. Scale bar, 50 µm. (B) Number of TUNEL-positive cells per seminiferous tubule (n = 6, *p<0.05). (C) Light micrographs of epox-embedded and toluidine blue-stained testicular sections from control and Ctnnb1 FΔ mice. Tubular profiles from a control mouse testis showing Sertoli cells and germ cells at various phases of development that support normal spermatogenesis (panel a). Tubular profiles from a Ctnnb1 FΔ mouse showing epithelial vacuolization and complete loss of elongated spermatids (panels b and c). Scale bar, 50 µm.