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. 2011 Nov 18;6(11):e27898. doi: 10.1371/journal.pone.0027898

Figure 3. Effects of combination of budesonide and formoterol on IFNα-induced by rhinovirus.

Figure 3

Cytokines produced by PBMC from healthy (A) and asthmatic (B) donors cultured for 24 h with RV16 in the presence of budesonide (Bud, 10−8 M) and/or formoterol (Form,10−8 M) as indicated. Box and whisker plots show median, interquartile range, and 10th and 90th percentiles for data from 12 donors in each subject group. Significant differences by Friedman ANOVA and Dunn's multiple comparison test for unstimulated versus RV16-stimulated cultures (+++, p<0.005) and between RV16-stimulated and RV16-stimulated cultures treated with budesonide and/or formoterol (***, p<0.001).