Figure 4. Levels of CCL2, CXCL1, and CXCL5 in TCM correlate with CD83 expression and IL-12p70 secretion.
Concentrations of CCL2, CXCL1, CXCL5 and VEGF in tumour conditioned media of 21 colorectal cancer patients were measured by ELISA. The concentrations of CCL2, CXCL1 and CXCL5 correlated with expression of CD83 on DCs treated with TCM (A). CCL2, CXCL1 and CXCL5 inversely correlated with secretion of IL-12p70 from dendritic cells treated with the TCM (B). The Spearman rank correlation test was used.