Figure 3. TLR4 deficiency attenuated AngII-induced vascular pathologies in LDLR−/− mice.
(A) AAAs were defined by measuring maximal external width of abdominal aortas. (B) Percent atherosclerotic lesion area was determined on aortic arches and thoracic aortas. Triangles represent individual mice. Circles represent means, and bars are SEM. * denotes P<0.001 by Mann-Whitney Rank Sum analysis.