Fig. 1.

BD1047 or (+)-pentazocine given intrathecally did not affect tail-flick latency. Groups of mice were injected intrathecally with BD1047 (10 μg), (+)-pentazocine (10 μg) or vehicle and the tail-flick responses were measured before and 45 min after injection. Each column represents the mean and the vertical bar represents the SEM with 8 to 9 mice in each group. Two-way ANOVA followed by Bonferroni post-test was used to test the difference between groups;