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. 2011 Nov;164(8):766–781. doi: 10.1016/j.chemphyslip.2011.09.004

Fig. 1.

Fig. 1

New anticancer drugs (1940s-06/2006) subdivided by source adapted from (Newman and Cragg, 2007): (B) biological; (N) natural product; (ND) derived from natural product – semisynthetic modifications; (S) synthetic drug; (S/NM) synthetic/natural drug mimic; (S*) made by total synthesis; (S*/NM) made by total synthesis/natural drug mimic; (V) vaccine.