Table 1.
Group | Sample | Day post-transplant | Viral load copies/ml | Total Clones | Unique Clones | Dominant Genotype | Coinfection | Recombinants | |
---|---|---|---|---|---|---|---|---|---|
Plasma | Urine | ||||||||
Viremia/nephropathy | 1a | 868 | 8.13E+03 | 1.50E+09 | 20 | 17 | Ia | none | |
1b | 418 | 1.37E+05 | 3.90E+08 | 20 | 12 | Ia | none | ||
2a | 192 | 1.12E+04 | 3.83E+09 | 20 | 3 | Ib2 | none | ||
2b | 450 | 3.21E+03 | 6.28E+07 | 20 | 4 | Ia | none | ||
3a | 81 | 1.03E+05 | 6.79E+09 | 20 | 6 | II | none | ||
3b | 70 | 1.53E+05 | 3.78E+09 | 22 | 10 | II/20 | none | I-II/1, II-I/1 | |
4 | 316 | 3.27E+03 | 7.30E+07 | 20 | 12 | Ib2 | none | ||
5 | 167 | 5.26E+03 | 1.02E+08 | 20 | 7 | Ib1 | none | ||
6 | 257 | 4.66E+05 | 3.20E+09 | 20 | 17 | Ib2 | none | ||
7 | 175 | 8.02E+04 | 3.86E+08 | 20 | 9 | Ib1 | none | ||
8** | 161 | 9.52E+03 | 1.42E+08 | 21 | 13 | II/20 | 1b1/1 | ||
9** | 208 | 3.31E+03 | 1.05E+09 | 20 | 4 | Ib2 | none | ||
10** | 196 | 1.72E+04 | 6.46E+06 | 20 | 11 | Ib2 | none | ||
11** | 914 | 1.26E+05 | 1.06E+10 | 20 | 7 | Ib2 | none | ||
Transplanted-viruria | 12 | 13 | 0 | 6.43E+05 | 22 | 19 | Ib1/20 | Ia/2 | |
13 | 40 | 0 | 2.50E+04 | 20 | 10 | II/13 | Ib2/2, Ib1/4, Ia/1 | ||
14 | 2737 | 0 | 2.20E+04 | 19 | 17 | Ib2/9 | Ia/1, Ib1/3, II/4 | II-I-II/1, II-I/1 | |
15 | 20 | 0 | 1.98E+03 | 20 | 16 | Ib2/14 | II/2, 1b1/1 | II-I/1, I-II/1, IV-I/1 | |
16 | 11 | 0 | 1.08E+03 | 18 | 13 | II/16 | 1b2/1 | II-I/1 | |
17 | 483 | 0 | 3.68E+03 | 20 | 15 | IV | none | ||
18 | 328 | 0 | 6.45E+03 | 20 | 16 | Ia/18 | II/1 | I-II/1 | |
Healthy-viruria | 19 | N/A | 0 | 9.90E+03 | 20 | 8 | Ib2 | none | |
20 | N/A | 0 | 4.40E+03 | 20 | 12 | IV/17 | Ia/1 | IV-I/2 | |
21 | N/A | 0 | 3.22E+04 | 20 | 15 | II/14 | none | I-II/1, IV-II/1, II-I/1, II-IV/2, IV-II/1 | |
22 | N/A | 0 | 3.78E+03 | 20 | 16 | Ib2 | none | ||
23 | N/A | 0 | 1.86E+03 | 20 | 15 | IV/17 | II/1 | II-IV/2 | |
24 | N/A | 0 | 2.78E+03 | 20 | 16 | Ib2 | none | ||
25 | N/A | 0 | 1.01E+04 | 16 | 15 | IV/4 | 1b2/1, II/1 | II-IV/3, IV-II/3, I-IV/1, I-II-I/1, I-II/1, I-II-IV/1 |
The number of clones corresponding to each dominant, co-infecting or recobminant genotype is indicated after the slash, wherever this number is not identical to the total number of clones sequenced. Parent sequences contributing to recombination are separated by a dash and are listed in the order in which they are recombined. The number after the slash indicates the number of recombinants found (totals 29).
Biopsy proven polyomavirus nephropathy.