Table 1.
Patient characteristics
| Characteristic | No AKI (N=160) | AKI (N=60) | P-value** |
|---|---|---|---|
| Age, years | 3.3 (0.5, 6.0) | 0.6 (0.4, 1.8) | < 0.0001 |
| Male, n (%) | 84 (53) | 26 (43) | 0.23 |
| White, n (%) | 142 (89) | 52 (87) | 0.67 |
| Prior surgery, n (%) | 76 (48) | 24 (40) | 0.32 |
| Bypass time, min | 92 (67, 127) | 113 (84, 172) | 0.003 |
| Baseline Scr, mg/dl | 0.4 (0.4, 0.6) | 0.3 (0.2, 0.4) | < 0.0001 |
| Baseline eCCL, ml/min/1.73m2 | 81.8 (65.0, 99.1) | 110.6 (84.0, 144.6) | < 0.0001 |
| Baseline urine NGAL, ng/ml | 8.5 (4.0, 12.5) | 16.0 (10.0, 24.0) | < 0.0001 |
| Baseline urine IL-18, pg/ml | 1.2 (0.0, 8.1) | 0.9 (0.0, 10.0) | 0.65 |
| Baseline urine KIM-1, pg/ml | 193.9 (83.8, 301.4) | 211.5 (96.2, 377.9) | 0.43 |
| Baseline urine FABP, ng/ml | 7.3 (2.3, 27.4) | 10.6 (4.2, 31.2) | 0.34 |
| % Scr change | 0.0 (0.0, 25.0) | 77.5 (64.6, 108.3) | < 0.0001 |
| Hospital stay, days | 5 (3, 7) | 7 (5, 14) | < 0.0001 |
| Ventilator, days | 1 (1, 2) | 2 (1, 2) | < 0.0001 |
| Inotrope score | 0.0 (0.0, 0.0) | 0.0 (0.0, 7.1) | 0.19 |
| Death, n (%) | 0 (0) | 1 (2) | 0.27 |
| RACHS score, n (%) | |||
| 1 | 20 (13) | 4 (7) | |
| 2 | 68 (43) | 29 (48) | |
| 3 | 60 (38) | 24 (40) | 0.14 |
| 4 | 9 (6) | 0 (0) | |
| 5 | 2 (1) | 1 (2) | |
| 6 | 1 (1) | 2 (3) | |
| pRIFLE, n (%) | |||
| R | --- | 27 (45) | --- |
| I | --- | 21 (35) | |
| F | --- | 12 (20) | |
| Duration of AKI, days | --- | 2 (2, 3) | --- |
| Dialysis (%) | 0 (0) | 0 (0) | --- |
Median (interquartile range, IQR) reported for continuous variables, p-values from Wilcoxon rank sum test. Frequency (proportion) reported for categorical variables, with p-values from χ2 test or Fisher’s exact test. pRIFLE and Duration of AKI reported for AKI patients only.