Skip to main content
. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Diabetologia. 2011 Apr 12;54(7):1756–1765. doi: 10.1007/s00125-011-2143-3

Figure 3.

Figure 3

Representative image of propidium iodide staining indicating an apoptotic nucleus (arrow) and non-apoptotic nuclei (arrow heads), propidium iodide = red, insulin = green (a). Beta-cell apoptosis (% apoptotic beta cells/total cells) in non-transgenic (open bars) and hIAPP transgenic (solid bars) islets cultured for 48 hours in 16.7 mmol/l glucose with no drug (control), exendin-4 or diazoxide (b), no drug (control) or KCl (c) or no drug (control) or somatostatin (d). *p<0.05 vs. control, †p<0.05 vs. non-transgenic, n=6–9.