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Beta-cell area/islet area (% insulin area/islet area) in non-transgenic (open bars) and hIAPP transgenic (solid bars) islets cultured for 48 hours in 16.7 mmol/l glucose with no drug (control), exendin-4 or diazoxide (a), no drug (control) or KCl (b) or no drug (control) or somatostatin (c). *p<0.05 vs. control, †p<0.05 vs. non-transgenic, n=6–8 (non-transgenic) and n=8–9 (hIAPP transgenic).
