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AG1295 and PP2 had no effect on KIR2.3 channels. (A) KIR2.3 current traces recorded with the voltage protocol as shown in inset of Figure 4A in a representative cell before (control) and after addition of 10 µM AG1295. (B) KIR2.3 current traces recorded in a typical experiment before (control) and after addition of 10 µM PP2. (C) Summary values of KIR2.3 current (−120 mV) as percent control, in cells before (control) or after 10 µM AG1295 (n = 5) or 10 µM PP2 (n = 5).
