DTT potentiation is reversed by oxidizing agent DTNB. A. Representative traces of currents evoked by extracellular [H+] (pH 6.0) in VSMCs before and after DTT pretreatment and following sequential treatment with 1 mM DTT and 1 mM DTNB (time bar not drawn to scale). Group data of the effect of DTT followed by DTNB pretreatment on the normalized peak amplitude (B) and accumulated currents (C, area under curve, AUC) induced by extracellular [H+], (n= 6, 7 and 7, respectively). ∗Significantly different, p<0.05.