GSH pretreatment potentiates acid-induced currents. A. Representative traces of currents evoked by extracellular [H+] (pH 6.0) in VSMCs before GSH pretreatment (control), and after 5-6 min GSH 0.5 and 2 mM pretreatment (n=9 and 10, respectively). Group data of the peak amplitude (B), and normalized accumulated current (C, area under curve, AUC) induced by extracellular [H+]. ∗Significantly different, p<0.05.