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a Representative laser Doppler images of Cx37–/– and Cx40–/– animals were obtained before and 1 day after surgery of surgical (box) and control limbs (scale bar = 1 cm). Total limb flow (b) and size (c) of perfused areas (both parameters normalized to the control limb) were elevated in Cx37–/– mice (n = 8) and reduced in Cx40–/– mice (n = 12) relative to WT (n = 8) throughout the 14-day recovery period. Asterisks denote a significant difference versus WT at the specified time point.
