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. 2011 Nov 14;1(2):e000216. doi: 10.1136/bmjopen-2011-000216

Table 1.

Characteristics of the derivation and validation cohorts

Variables Derivation cohort (n=192) Validation cohort (n=593) p Value
Age (years), mean±SD 61±19.6 60.8±20.9 0.92
Gender, male (%) 100 (52) 308 (51.8) 0.97
APACHE III score, median (IQR) 56 (40–75) 51 (32–71) <0.05
Most common APACHE IV diagnosis groups; n (%)
  1. OD, 26 (13.5)

  2. RESPOTH, 19 (9.9)

  3. BACPNEU, 18 (9.4)

  1. OD, 129 (21.8)

  2. BACPNEU, 53 (9.0)

  3. GIBLEED, 49 (8.3%)

ICU mortality (%) 9.4 4.7 0.01
Hospital mortality (%) 16.1 12.3 0.17
ICU length if stay, median (IQR) 1.6 (0.8–3.0) 1.1 (0.7–1.9) <0.01
Hospital length of stay, median (IQR) 5.6 (2.6–10.1) 3.7 (1.8–6.8) <0.01

APACHE, Acute Physiology and Chronic Health Evaluation; BACPNEU, pneumonia, bacterial or other; GIBLEED, bleeding, GI, upper or unknown location; ICU, intensive care unit; OD, overdose, drug withdrawal; RESPOTH, sleep apnoea, atelectasis, pulmonary haemorrhage/haemoptysis, haemothorax, primary/idiopathic hypertension—pulmonary, near-drowning accident, pneumothorax, respiratory—medical, other, restrictive lung disease (ie, sarcoidosis, pulmonary fibrosis), smoke inhalation, weaning from mechanical ventilation (transfer from another unit or hospital only).