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. 2011 Jan 21;173(1):60–66. doi: 10.1016/j.jviromet.2011.01.007

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Copyright © 2011 Elsevier B.V. All rights reserved.

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Fig. 1 — Algorithm of clinical reference diagnostic test in clinical virology laboratory for respiratory samples. Diagnostic algorithm used in clinical virology laboratory to detect respiratory viruses mainly divided into respiratory season or non-respiratory season. Respiratory season defined as October to the following January (October to November for RSV, December to January for influenza). Immunochromatographic assays were used in respiratory season as the sole screening test for RSV and influenza, which will stop the testing algorithm if results are positive. Respiratory panel cocktail DFA tests serve for adenovirus, influenza A and B, parainfluenza types 1–3 and RSV, which will stop the testing algorithm if results are positive in non-respiratory season or for those screened negative by immunochromatographic assays in respiratory season as well. RSV, respiratory syncytial virus; PIV, parainfluenza virus; HSV, herpes simplex virus; CMV, cytomegalovirus; hMPV, human metapneumovirus; DFA, direct fluorescent antibody test; CPE, cytopathic effect; RBC, red blood cells.