Figure 4.

Whole mount of paratransgenic sand fly. A: shows the auto-fluorescence associated with the outer carapace and specific GFP fluorescence within the sand fly. B: shows GFP-specific fluorescence signal uncoupled from the background. These 4x-images were captures using a Nuance multispectral imaging system. GFP-specific fluorescence is contained to the midgut chamber of the adult sand fly with no evidence of transfer to other regions of the insect. Figure is adapted from Hurwitz et al, The paratransgenic sand fly: a platform for control of Leishmania transmission. Parasit Vectors, 2011, 4:e82