Survival curves of 7,635 patients with metastatic melanoma at distant sites (stage IV) subgrouped by (A) the site of metastatic disease and (B) serum lactate dehydrogenase (LDH) levels. LDH values are not used to stratify patients. Curves in (A) are based only on site of metastasis. The number of patients is shown in parentheses. SQ, subcutaneous.
From Balch CM, Gershenwald JE, Soong S, et al, Journal of Clinical Oncology 27(36): 6199-206, 2009, with permission.