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(A) Food intake, (B) body weight, (C) energy expenditure as measured by CO2 produced (VCO2), (D) respiratory exchange ratio (CO2 produced/O2 consumed) (RER), (E) locomotor activity, and (F) metabolic efficiency plots in 2 month old WT and Foxo1KR/KR mice maintained on standard chow diet. n=8 for each genotype and each experiment. *=P<0.05 by 2-way ANOVA. Data are presented as means ± SEM.
