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. 2011 Oct 3;29(32):4294–4301. doi: 10.1200/JCO.2011.36.4596

Fig 1.

Fig 1.

Prevalence of human papillomavirus (HPV) infection in oropharyngeal cancers across four calendar periods (1984 to 1989, 1990 to 1994, 1995 to 1999, and 2000 to 2004) is shown for any HPV infection as determined by (A) the Inno-LiPA assay, (B) HPV16 viral load, (C) HPV16 E6/E7 oncogene expression, and (D) HPV16 in situ hybridization. Solid lines and circles represent observed prevalence estimates. Dotted lines and squares represent prevalence estimates corrected for potential loss in assay sensitivity because of the age of the specimens. The number of specimens evaluable for each assay is shown below the x-axis.