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. 2011 Sep 9;20(24):4786–4796. doi: 10.1093/hmg/ddr416

Table 3.

The top-scoring functional networks of genes nominated by analysis of SZ-discordant twin pairs and BD-discordant twin pairs

Associated network functions Network score
Top SZ networks
 1 Nervous system development and function, cellular development, reproductive system development and function 73
 2 Cell signaling, nucleic acid metabolism, small-molecule biochemistry 39
 3 Embryonic development, organ development, organ morphology 30
Top BD networks
 1 Neurological disease, developmental disorder, genetic disorder 67
 2 Psychological disorders, genetic disorder, nutritional disease 48
 3 Gene expression, RNA post-transcriptional modification, organismal development 18

The network score is a numerical value used to rank networks according to their degree of relevance to the network eligible molecules in the gene list. A number of functional networks directly related to psychosis were highlighted by these analyses.