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. 2009 Jun;23(6):1721–1727. doi: 10.1096/fj.08-127548

TABLE 3.

Serum and liver N-Hcy-protein and tHcy levels in Tg-I278T and Tg-hCBS mice

Genotype N-Hcy-protein
tHcy
Plasma (μM) Liver (pmol/mg of protein) Plasma (μM) Liver (pmol/mg of protein)
Tg-I278T Cbs−/− (n=4) 16.6 ± 4.1 1857 ± 452 272 ± 50 5680 ± 1777
Tg-I278T Cbs+/− (n=2) 2.62 ± 1.73 161 ± 19 5.0 ± 2.6 110
Tg-I278T Cbs+/+ (n=2) 1.56 ± 0.25 163 ± 0.0 1.9 ± 1.6 75 ± 7.1
Tg-hCBS Cbs−/− (n=4) 10.8 ± 2.1 562 ± 132 167 ± 40 582 ± 326
Tg-hCBS Cbs+/− (n=4) 2.6 ± 0.8 165 ± 24 6.1 ± 2.4 153 ± 21