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. 2011 Nov 21;6(11):e26545. doi: 10.1371/journal.pone.0026545

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Panel A depicts selection of 21 patients with culture-confirmed tuberculosis (patients) from among 179 tuberculosis (TB) suspects enrolled in a previously described study [27]. Panel B depicts selection of 24 subjects at low risk for Mtb infection (controls) from among 866 Navy recruits enrolled in a previously described study [28]. No significant differences in characteristics of those selected or not selected were observed. Plasma samples from all 21 patients and 24 controls were assessed by the commercial ELISA, QuantiFERON-TB Gold test (QFT-G). Plasma samples from 6 patients and 10 controls were assessed by the in-house MMIA. Plasma samples from 6 patients and 7 controls were assessed by the microarray. Plasma samples from 12 patients and 12 control subjects were assessed by the commercial MMIA.