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. 2011 Nov 21;6(11):e26545. doi: 10.1371/journal.pone.0026545

Table 3. Comparisons of IFN-γ responses to different antigens measured by commercial ELISA among patients with culture-confirmed tuberculosis.

Cytokine ESAT-6 ESAT-6 ESAT-6 ESAT-6 CFP-10 CFP-10 CFP-10 TB7.7 TB7.7 ESAT-6+CFP-10
vs. vs. vs. vs. vs. vs. vs. vs. vs. vs.
CFP-10 TB7.7 ESAT-6+CFP-10 ESAT-6+CFP-10+TB7.7 TB7.7 ESAT-6+CFP-10 ESAT-6+CFP-10+TB7.7 ESAT-6+CFP-10 ESAT-6+CFP-10+TB7.7 ESAT-6+CFP-10+TB7.7
IFN-γ 61 61 61 61 128 128 128 3 3 187
vs. vs. vs. vs. vs. vs. vs. vs. vs. vs.
128 3 187 202 3 187 202 187 202 202
(0.794) (<0.001) (0.007) (0.006) (<0.001) (0.005) (0.005) (<0.001) (<0.001) (0.327)

Median IFN-γ responses (from Table 2) to early secreted antigenic target-6 (ESAT-6), culture filtrate protein 10 (CFP-10), TB7.7, and combinations of these antigens for patients with culture-confirmed tuberculosis (patients) are listed with p values in parenthesis calculated by Mann-Whitney U Rank Sum test. Significant differences (p<0.05) are indicated in bold type.