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. 2011 Nov 21;6(11):e28036. doi: 10.1371/journal.pone.0028036

Figure 5. Insulin/IGF-1 signaling does not influence FLA toxicity.

Figure 5

Life spans of N2, daf-2(e1370), and daf-16(mu86) animals after continuous treatment with DMSO or FLA under control-fed conditions starting at day 4 of adulthood. Mutation of daf-2 and daf-16 extended and shortened life span, respectively, compared to N2 in DMSO treated samples. N2, daf-2(e1370), and daf-16(mu86) animals displayed significantly shortened life spans when treated with FLA. Summary data and statistics for both pooled and individual experiments are shown in Table S3.