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Coexpression of patterns of MYC activation and estrogen independence predicts poor outcome following adjuvant tamoxifen. LOI164 (A), LOI181 (B), and MDACC298 (C) patients were stratified by MYC score (tertiles) and LTED score (median) as in Figs. 3-4. Patients demonstrating a high score in neither (NONE), either (MYC/LTED), or both scores (MYC+LTED) were grouped, and Kaplan-Meier survival curves were compared by log-rank test.
