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MYC is required for hormone-independent cell proliferation. Cells transfected with siRNA targeting MYC or non-silencing control (siCtl) were treated with 10% DCC-FBS, and adherent cells were counted after 6 days. Data are presented as % siCtl, mean of triplicates ± SD. *p<0.01 by t-test compared to siCtl. B) MYC and actin immunoblots of lysates from the same batches of cells used in (A).
