Figure 5.

Gene expression on chromosome 13 differs for the monosomic and disomic melanin variants. A heat map is shown for the profiles of gene expression of CBS7779-B4 compared to CBS7779-W2 as detected by microarray anlaysis. A total of six arrays including three biological repeats and dye-swap sets were performed. Each column (lane 1 to 6) represents a microarray experiment and each row represents the expression of a gene on the array arranged by its chromosomal position. The relative expression levels are depicted as shown by the color bar. A summary of the numbers of differentially regulated genes for each chromosome in the disomic strain CBS7779-W2, compared to those in CBS7779-B4, is given on the right.