Table 4.

Predictors for clinical worsening during follow-up using Cox proportional hazards

	HR (univariate)	P
Male	0.54 (0.18–1.68)	0.29
BMI	1.02 (0.89–1.16)	0.80
Age	1.03 (0.98–1.08)	0.23
NYHA FC	0.73 (0.32–1.65)	0.45
6-MWD	1.00 (1.00–1.00)	0.79
PAP mean	0.98 (0.94–1.03)	0.47
PVR	1.00 (1.00–1.00)	0.36
CO	1.69 (0.89–3.32)	0.13
NT-pro BNP	1.00 (1.00–1.00)	0.04
VC	0.92 (0.58–1.47)	0.73
FEV1	1.01 (0.98–1.05)	0.53
pO2	0.95 (0.72–1.26)	0.73
Saturation	1.04 (0.88–1.23)	0.64

CW = clinical worsening; HR = hazard ratio; BMI = body mass index; NYHA FC = New York Heart Association Functional Class; 6-MWD = six minute walk distance; PAP mean = mean pulmonary artery pressure; PVR = pulmonary vascular resistance; CO = cardiac output; NT-pro BNP = N-terminal pro brain natriuretic peptide; Creat = creatinine; VC = vital capacity; FEV1 = forced expiratory volume in 1 s; pO2 = O2 pressure