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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Gastroenterology. 2011 Sep 3;141(6):2039–2046. doi: 10.1053/j.gastro.2011.08.041

Figure 3. Haplotyping of individuals in families 1, 3 and 4.

Figure 3

Left, Map of the UNC5C locus indicating the approximate position of the different SNP markers in this region. Most are intronic. The position of the markers is indicated. Right, Pedigrees of individuals genotyped in families 1, 3 and 4. Individual identifiers as in Figure 2B. Location of markers and the A628K mutation in exon 11 are given on the left. Arrows indicate exonic markers. A common disease-associated haplotype (red) covering 108692 bp and comprising the A628K mutation is shared by all tested mutation-positive individuals.