Exacerbation of CNV lesions (light green) by CEP-MSA in a mouse model of CNV. Representative photographs of mouse choroids at 14 days after laser photocoagulation and subretinal injections of (a) PBS, (b) MSA (1 μg), (c) CEP-MSA (1 μg), and (d) VEGF (20 ng). This research was originally published in PNAS. Ebrahem, Q., Renganathan, K., Sears, J., Vasanji, A., Gu, X., Lu, L., Salomon, R. G., Crabb, J. W. and Anand-Apte, B. (2006) Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration. Proc Natl Acad Sci U S A 103, 13480–13484. © The National Academy of Sciences of the United States of America.