The effects of AAL-993, anti-CEP mAb, or isotype control IgG2a on tumor size (left panel) and their vascularization (right panel). This research was originally published in Nature. West, X. Z., Malinin, N. L., Merkulova, A. A., Tischenko, M., Kerr, B. A., Borden, E. C., Podrez, E. A., Salomon, R. G. and Byzova, T. V. (2010) Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands. Nature 467, 972–976. © Nature Publishing Group.