Table 1.
Characteristics of study groups
| Age (years) | Trabecular bone formation rate (BFR)(μm3/μm2/year) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Group | N | Laboratory | Osteoporotic | Bisphos- phonate | Fracture | Age- matched | Range | Mean (SD) | Range | Mean (SD) |
| Y gN | 20 | HFH | N | N | N | N | 20–40 | 31.6a (5.6) | 0–23.3 | 13.5c (6.9) |
| AMN | 12 | HFH | N | N | N | Y | 49–74 | 63.8b (8.5) | 0.6–42.3 | 14.8c (13.7) |
| OP | 11 | HFH | Y | N | lumbar vertebral |
Y | 53–76 | 65.5b (7.7) | 0.5–67.1 | 16.7c (19.4) |
| SSBT | 12 | HFH (7), SMC (5) | Y | Y | atypical femur |
Y | 49–77 | 64.1b (9.3) | 0–1.00 | 0.3d (0.4) |
YgN - Young normal
AMN - Age-matched normal
OP - Osteoporotic
SSBT - Severely suppressed bone turnover
HFH - Henry Ford Hospital, Detroit, MI
SMC - Southwestern Medical Center, Dallas, TX
a
values that do not share alphabetic superscripts within a column are statistically different (p<0.05)
b
values that do not share alphabetic superscripts within a column are statistically different (p<0.05)
c
values that do not share alphabetic superscripts within a column are statistically different (p<0.05)
d
values that do not share alphabetic superscripts within a column are statistically different (p<0.05)