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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: J Immunol. 2011 Oct 31;187(11):5783–5794. doi: 10.4049/jimmunol.1100484

Figure 5. Abnormal cytokine production upon efferocytosis by PTEN-/- macrophages.

Figure 5

Thioglycollate-elicited peritoneal macrophages from wild type and PTEN-/- mice were stimulated with or without lipopolysaccharide (LPS) in the presence or absence of apoptotic cells for 16 hrs. Culture supernatants were analyzed for anti-inflammatory cytokines IL-10 (A), proinflammatory cytokine IL-6 (B), and TNFα (C) by ELISA. Data is a representative of 4 independent experiments. Results shown are means ± SD. * p<0.0005. (D) Constitutive phosphorylation of GSK3β (Ser9) in resting macrophages from wild type and PTEN-/- mice. Actin was used as loading control.