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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: J Immunol. 2011 Nov 4;187(11):5510–5514. doi: 10.4049/jimmunol.1102243

Figure 2. Irreversible tissue retention of lung memory CD4 T cells.

Figure 2

Host mice containing Thy1.1+ lung or spleen-derived HA-specific memory CD4 T cells as in Fig. 1C were surgically conjoined to syngeneic BALB/c partner mice in parabiosis experiments (see methods). (A) Frequency of spleen and lung-derived CD4+Thy1.1+ HA-specific memory CD4 T-cells (of total CD4 T cells) in tissues of host and parabiont partner mice after 8 days conjoined. (B) Percent distribution of HA-specific memory CD4 T cells recovered from host and partner mouse tissues calculated as in Fig. 1D. Results are compiled from eight parabiotic mouse pairs/group and representative of 2 independent experiments. Significant differences between lung and spleen memory migration are indicated by *** (p <0.005).