Table III.

Steady State Pharmacokinetic Parameters (Using Total Concentration of Telapristone and CDB-4453) for 500 Simulated Subjects at 25 mg

25 mg Steady state
Parameter	Median	5th and 95th Percentiles
High-clearance group
C max (nmol/L)	1,273	538–2,750
T max (h)	2.00	0.750–7.00
AUCtot 0–24 (nmol*h/L)	9,141	5,507–16,288
Low-clearance group
C max (nmol/L)	2,308	1,099–5,266
T max (h)	2.00	0.25–16
AUCtot 0–24 (nmol*h/L)	22,458	11,238–46,691