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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: J Immunol. 2011 Oct 26;187(11):5558–5567. doi: 10.4049/jimmunol.1101724

Figure 3. B and T cells together mediate the expansion phase.

Figure 3

μMT mice (A–E) and βδ TCR−/− (F–J) and controls were immunized with OVA/CFA on Day 0 and draining popliteal nodes were examined on day 5. CD4 and CD8 T cell-depleted μMT mice (K–M) were immunized as above but examined on day 4. (A, F, K) Lymph node cellularity. (B, G, L) Number of endothelial cells in each subset. (C, H) Proliferation rate of endothelial cells in each subset. (D, I, M) Numbers of gp38+ FRCs. (E, J) Proliferation rate of gp38+ FRCs. For μMT mice and βδ TCR−/−, n=5–6 mice in each group over 3 experiments. For T cell-depleted μMT mice, n=5 mice in each group over 2 experiments. * indicates p value<.05 and ** indicates p value<.01 in comparison to the same cells in unimmunized controls of the same genotype using t-test; + indicates p-value<.05 and ++ indicates p-value<.01 in comparison to the same cells in WT mice receiving same treatment.