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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: J Immunol. 2011 Oct 26;187(11):6002–6010. doi: 10.4049/jimmunol.1100232

Figure 3. The role of MyD88 and TLR9 in detecting live S. aureus.

Figure 3

(A and B) BMDM from WT C57BL/6 mice and MyD88−/− mice were infected at an MOI=6 and TNF-α was assessed in the supernatant at 4 (A) and 18 (B) hours. All responses were MyD88-dependent. (C and D) BMDM from C57BL/6 and TLR9−/− mice were infected at and MOI=25. After 2 (C) and 18 (D) hours, TNF-α levels in the supernatant were measured by ELISA. TLR9 contributes to later responses induced by ΔoatA-SA. All data represent triplicates + SD. Statistics were done by student t-test * p<0.05, ** p<0.001.