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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Cytokine. 2011 Oct 22;56(3):804–810. doi: 10.1016/j.cyto.2011.09.028

Fig. 4.

Fig. 4

Comparison of the pharmacokinetic profile of IL-15wt and IL-15N72D:IL-15RαSu/Fc complex following intravenous administration in CD-1 mice. The anti-IL-15 Ab ELISA measures the concentration of IL-15wt (■). The anti-IL-15 Ab ELISA measures the concentration of the intact IL-15N72D:IL-15RαSu/Fc molecule (△), whereas the anti-human IgG Fc Ab ELISA measures serum concentration of the IL-15RαSu/Fc fusion protein (▼). The observed concentrations are represented by symbols and the model-fitted curves are represented by lines.