Table 1.
Basic characteristics and physiological data of patients according to their study groupsa
| AIS score, head <3 | AIS score, head ≥3 | |||||
|---|---|---|---|---|---|---|
| Patient characteristics | FFP:pRBC ratio ≤1:2 | FFP:pRBC ratio >1:2 | P value | FFP:pRBC ratio ≤1:2 | FFP:pRBC ratio >1:2 | P value |
| Number of patients (%) | 212 (17%) | 426 (34.1%) | 167 (13.4%) | 445 (35.6%) | ||
| Mean age, yr (±SD) | 45.9 ± 20 | 42.0 ± 17.2 | 0.049 | 40.5 ± 19.2 | 40.2 ± 18.2 | 0.947 |
| Males, n (%) | 149 (70.3%) | 330 (77.5%) | 0.048 | 111 (66.5%) | 314 (70.6%) | 0.327 |
| Blunt trauma mechanism, n (%) | 191 (90.1%) | 379 (89%) | 0.722 | 158 (94.6%) | 417 (93.7%) | 0.676 |
| Mean ISS, points (±SD) | 36.7 ± 15.3 | 35.4 ± 13.5 | 0.532 | 49.5 ± 14.9 | 47.2 ± 14.1 | 0.143 |
| Mean GCS at trauma scene, points | 10 | 12 | 0.001 | 7 | 7 | 0.571 |
| Mean HR at trauma scene, beats/min (±SD) | 105 ± 31 | 106 ± 25 | 0.907 | 106 ± 33 | 105 ± 28 | 0.240 |
| Mean HR at hospital admission, beats/min (±SD) | 105 ± 27 | 102 ± 26 | 0.222 | 103 ± 31 | 104 ± 26 | 0.686 |
| Mean systolic BP at trauma scene, mmHg (±SD) | 91 ± 34 | 95 ± 31 | 0.245 | 90 ± 35 | 93 ± 35 | 0.792 |
| Mean systolic BP at hospital admission, mmHg (±SD) | 93 ± 36 | 95 ± 30 | 0.411 | 92 ± 34 | 96 ± 30 | 0.313 |
| Mean Hb, g/dl (±SD) | 8.0 ± 2.7 | 8.4 ± 2.8 | 0.09 | 8.0 ± 2.9 | 8.4 ± 3.0 | 0.13 |
| Mean BE, mM/l (±SD) | -8.9 ± 6.8 | -7.0 ± 5.9 | 0.08 | -9.3 ± 6.5 | -7.3 ± 6.4 | 0.01 |
| Mean PTT, seconds (±SD) | 51.9 (±32.8) | 50.9 (±31.1) | 0.63 | 72.3(±49.3) | 60.7(±37.5) | 0.06 |
| Mean quick, % (±SD) | 54 (±23.7) | 56 (±23.4) | 0.33 | 54 (±24.2) | 53 (±23.0) | 0.69 |
| Mean platelets, nl (±SD) | 158 (±77.7) | 165 (±75.6) | 0.30 | 152 (±74.0) | 160 (±71.6) | 0.23 |
| Coagulopathy, n (%) | 152 (87.4%) | 298 (82.3%) | 0.14 | 118 (90.1%) | 344 (88.4%) | 0.61 |
aAIS, Abbreviated Injury Scale; FFP, fresh frozen plasma; pRBC, packed red blood cell; SD, standard deviation; ISS, Injury Severity Score; GCS, Glasgow Coma Scale; HR, heart rate; BP, blood pressure; Hb, hemoglobin; BE, base excess; PTT, partial thromboplastin time. Coagulopathy was defined by the presence of at least one of the following conditions: PTT <38 seconds, Quick <70% and platelets <100,000/μl. In the TR-DGU the prothrombin time (PT) is documented as Quick's value where a value of <70% is equivalent to an INR (International Normalized Ratio) > 1.3.