Table 1.
Demographic dataa
| Patient demographics | ALI | Reference ventilated | Reference spontaneous |
|---|---|---|---|
| Number of patients | 78 | 43 | 31 |
| Median agens | 42 (23 to 51) | 27 (21 to 45) | 32 (22 to 44) |
| Sex (male/female)b | 61/17 | 37/6 | 19/12 |
| Median heightb, cm | 176 (173 to 180) | 175 (170 to 183) | 174 (168 to 183) |
| Median weightb, kg | 80 (74 to 90) | 75 (70 to 82) | 73 (59 to 85) |
| Median Body Mass Indexb, kg m-2 | 26 (23 to 28) | 24 (23 to 26) | 23 (21 to 24) |
| Median PaO2/FiO2, mmHg | 169 (95 to 240) | 560 (506 to 616)d | n.a. |
| Median Lung Injury Score | 2.3 (2.0 to 3.0) | n.a. | n.a. |
| Median Injury Severity Scorec | 36 (29 to 48) | 20 (12 to 26)d | 12 (6 to 16)d,e |
| Median AIS-T | 4 (4 to 4) | n.a. | n.a. |
| Median Thoracic Trauma Severity Scoreb | 11 (9 to 14) | n.a. | n.a. |
| Median Glasgow Coma Scale scorec | 11 (4 to 15) | 11 (7 to 15) | 15 (15 to 15)d,e |
| Median volume of intravenous fluids c, ml | 2,000 (1,125 to 3,000) | 1,000 (500 to 1,500)d | 1,000 (500 to 1,000)d |
| Median time to CTns, min | 122 (90 to 207) | 105 (79 to 129) | 100 (81 to 136) |
| Median ventilator-free daysb | 17 (4 to 23) | 27 (19 to 27) | n.a. |
| Median ICU-free daysb | 7 (0 to 17) | 22 (10 to 26) | n.a. |
aAll values are given as medians with interquartile ranges. ALI, patients with acute lung injury at admission; reference ventilated, mechanically ventilated patients with normal lungs; reference spontaneous, spontaneously breathing patients with normal lungs; Body Mass Index, weight in kilograms divided by the square of the height in meters; PaO2/FiO2, ratio of arterial partial pressure of oxygen to fraction of inspired oxygen; AIS-T, Abbreviated Injury Scale of the Thorax; time to CT, interval between trauma and computed tomography (CT); ventilator-free days, number of days without mechanical ventilation within a period of 28 days; ICU, intensive care unit; ICU-free days, number of days without ICU treatment within a period of 28 days; n.a., not applicable; ns, not significant. Positive end-expiratory pressure (PEEP) was 10 cmH2O in all mechanically ventilated patients except for five; in three patients, PEEP >10 cmH2O was already applied before admission and two patients were spontaneously breathing during CT. bNo statistical test performed. cP < 0.001 for the Kruskal-Wallis test over all groups. dP < 0.001 versus ALI. eP < 0.05 versus reference ventilated group.