Table 3.
Characteristics of studies included in meta-analysis
| Author: | Year | Study design | Population | Modality | Early (n) | Late (n) | Early criteria | Late criteria |
|---|---|---|---|---|---|---|---|---|
| Bouman [10] | 2002 | Randomised | Cardiac surgery/medical | CVVH | 35 | 36 | RRT within 12 hours if Urine Output <30 ml/hr | Urea >40 mmol/l or K >6.5 mmol/L |
| Sugahara [32] | 2004 | Randomised | Cardiac Surgery | CVVH | 14 | 14 | Urine Output <20 ml/hr | Urine Output <30 cc/hr |
| Liu [21] | 2006 | Prospective Cohort | Medical,Surgery | CRRT/IHD | 122 | 121 | Urea <27.1 mmol/L | Urea >27.1 mmol/L |
| Sabater [33] | 2008 | Prospective Cohort | Medical (Septic Shock) | CVVHF | 9 | 23 | Rifle Criteria (Risk, Injury)* | Rifle Criteria (Failure)** |
| Bagshaw [34] | 2009 | Prospective Cohort | Medical, Surgical | CRRT/IHD | 618 | 619 | Urea <24.2 mmol/L | Urea >24.2 mmol/L |
| Bagshaw [35] | 2010 | Prospective Cohort | Medical, Surgical | CRRT/IHD | 117 | 117 | Urea <23 mmol/L | Urea >23 mmol/L |
| Gettings [15] | 1999 | Retrospective Cohort | Trauma | CAVHD and CVVHD | 41 | 59 | Urea <21.4 mmol/L | Urea >21.4 mmol/L |
| Elahi [38] | 2004 | Retrospective Cohort | Cardiac surgery | CVVH | 28 | 36 | Urine Output <100 cc in 8 hrs | K >6 mmol/L, Cr >250 mmol/L |
| Dermirkilic [13] | 2004 | Retrospective Cohort | Cardiac Surgery | CVVHDF | 27 | 34 | Cr >400 μmol/L, Potassium >5.5 mmol/L | Oliguria |
| Andrade [36] | 2007 | Retrospective Cohort | Medical (ARDS/Sepsis) | IHD/SLED | 18 | 15 | On admission | At 24 hours |
| Wu [42] | 2007 | Retrospective Cohort | Surgical ALF | IHD/CVVH | 54 | 26 | Urea < 28.6 mmol/L | Urea >28.6 mmol/L |
| Manche [40] | 2008 | Retrospective Cohort | Cardiac Surgery | IHD | 56 | 15 | Hyperkalemia | U/O <0.5 ml/kg/hour |
| Iyem [39] | 2009 | Retrospective Cohort | Cardia Surgery | CVVH | 95 | 90 | RRT on admission | After 48 hours when anuric |
| Shiao [41] | 2009 | Retrospective Cohort | Surgery/Trauma | CVVH | 51 | 47 | Rifle Criteria (Risk)* | Rifle Injury, Failure** |
| Carl [37] | 2010 | Retrospective Cohort | Medical (sepsis) | CRRT/IHD | 85 | 62 | Urea <35.7 mmol/l | Urea >35.7 mmol/L |
Abbreviations: Cr = creatinine (μmol/L); K = potassium (mmol/L).
RIFLE Criteria Risk: Increase in serum Creatinine by 1.5 times or urine output <0.5 ml/kg/hour × 6 hours.
RIFLE Criteria Injury: Increase in serum Creatinine by 2 times or urine output <0.5 ml/kg/hour × 12.
RIFLE Criteria Failure: Increase in serum Creatinine by 3 times or urine output <0.3 ml/kg/hour × 24.