Table 3.

Areas under the receiver operating characteristic curve (95% confidence intervals) for prediction of fluid responsiveness (increase in cardiac index ≥10% (A) or ≥15% (B)) by baseline values, according to global ejection fraction

	GEF <20% (n = 12)			GEF ≥20% (n = 20)
	AUC	P-value	Cutoff	AUC	P-value	Cutoff
A
GEDVI	0.56 (0.39 to 0.73)	0.511	902	0.72 (0.58 to 0.83)	0.002	890
CVP	0.76 (0.59 to 0.88)	0.001	6	0.73 (0.60 to 0.84)	<0.001	2
PAOP	0.79 (0.57 to 0.93)	0.004	10	0.65 (0.46 to 0.81)	0.129	9
B
GEDVI	0.62 (0.44 to 0.77)	0.33	1279	0.89 (0.78 to 0.95)	<0.001	623
CVP	0.77 (0.60 to 0.89)	0.002	5	0.73 (0.60 to 0.84)	0.013	4
PAOP	0.84 (0.63 to 0.96)	<0.001	9	0.50 (0.32 to 0.69)*	0.98*	9

CVP, central venous pressure, mm Hg; GEDVI, global end diastolic volume index, mL/m²; GEF, global ejection fraction; PAOP, pulmonary artery occlusion pressure, mm Hg.

*P = 0.008 vs. AUC GEDVI; for A and low GEF: PAOP sensitivity 92%, specificity 60%, positive predictive value 75%, negative predictive value 86%; for normal GEF: GEDVI sensitivity 82%, specificity 56%, positive predictive value 42%, negative predictive value 89%; for B and low GEF: PAOP sensitivity 86%, specificity 69%, positive predictive value 55%, negative predictive value 92%; for normal GEF: GEDVI sensitivity 71%, specificity 94%, positive predictive value 63%, negative predictive value 93%.