Table 5.
Laboratory findings
| Day of ICU admission | IBPA | Control | P value | |
|---|---|---|---|---|
| Complete blood count | ||||
| White blood cell count (×109/L), mean (SD) | Day 1 | 21.0(14.0) | 9.4(3.7) | 0.012a |
| Day 4 | 17.5(5.6) | 10.6(13.9) | 0.101 | |
| Day 7 | 19.5(6.3) | 10.0(5.4) | 0.000a | |
| Neutrophilic granulocyte (%), mean (SD) | Day 1 | 90.2(6.3) | 84.3(10.0) | 0.053 |
| Day 4 | 89.4(7.7) | 79.3(10.7) | 0.004a | |
| Day 7 | 87.8(6.9) | 80.3(8.6) | 0.027a | |
| Arterial blood gas analysis | ||||
| pH, mean (SD) | Day 1 | 7.25(0.14) | 7.36(0.11) | 0.005a |
| Day 4 | 7.42(0.08) | 7.42(0.05) | 0.768 | |
| Day 7 | 7.42(0.10) | 7.42(0.05) | 0.995 | |
| PaCO2 (mm Hg), mean (SD) | Day 1 | 65.3(36.1) | 68.8(33.1) | 0.745 |
| Day 4 | 53.3(22.7) | 53.5(11.4) | 0.979 | |
| Day 7 | 47.9(22.4) | 49.2(12.9) | 0.845 | |
| Ratio of the PaO2 to FiO2, mean (SD) | Day 1 | 166.0(86.8) | 219.1(128.8) | 0.171 |
| Day 4 | 197.5(80.0) | 225.7(88.2) | 0.332 | |
| Day 7 | 199.9(72.3) | 236.8(83.8) | 0.255 | |
| Renal function | ||||
| Clearance of creatinine (ml/min), mean (SD) | Day 1 | 36.2(20.4) | 68.8(27.5) | 0.000a |
| Day 4 | 36.6(24.0) | 82.5(51.5) | 0.005a | |
| Day 7 | 33.3(32.3) | 77.6(50.4) | 0.021a | |
| Liver function | ||||
| ALT (U/L), median (IQR) | 52.5(36.5-95) | 28(20-43) | 0.003a | |
| AST (U/L), median (IQR) | 67(49-118.5) | 26.5(21.8-49.8) | 0.000a | |
| Coagulation | ||||
| APTT (s), median (IQR) | 34.8(28.4-49.3) | 28.5(26.2-37.7) | 0.046a |
ALT, alanine aminotransferase; APTT, activated partial thromboplastin time; AST, aspartate aminotransferase; FiO2, the fraction of inspired oxygen; SD, standard deviation; IQR, interquartile range; PaCO2, partial pressure of arterial carbon dioxide; PaO2, partial pressure of arterial oxygen. aP < 0.05.