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. 2011 Jan 6;15(1):R5. doi: 10.1186/cc9402

Table 6.

Results of first and two consecutive detections of galactomannan in serum of critically ill CORD patients

Single GM detection (95% CI) Two consecutive GM detections (95% CI) (n = 48)


Positive for a first test (n = 55) Positive for a second test (n = 48) At least one positive of the two consecutive tests Both positive for the two consecutive tests
Sensitivity (%) 46.2 (33.3-59.1) 50.0 (35.9-54.1) 53.8 (39.7-67.9) 41.7 (27.8-55.6)
Specificity (%) 83.3 (73.4-93.2) 93.5 (86.5-100) 81.0 (69.9-92.1) 93.5 (86.5-100)
PPV (%) 46.2 (33.3-59.1) 75.0 (62.7-87.3) 46.7 (32.6-60.8) 71.4 (58.7-84.1)
NPV (%) 83.3 (73.4-93.2) 82.9 (72.2-93.6) 85.0 (74.9-95.1) 80.6 (69.7-91.5)
TCR (%) 74.5 (63.0-86.0) 81.4 (70.4-91.4) 74.5 (62.2-86.8) 79.1 (67.9-90.3)

CORD, chronic obstructive respiratory disease; NPV, negative predictive value; PPV, positive predictive value; TCR, total consistent rate.