Table 2.

Association of Demographic, Reproductive History, Contraceptive Use, Sexual Behavior, and Clinical Variables and Incident HPV and HR-HPV Infection Status

	Any HPV infection		Any HR-HPV infection
Variable	OR (95% CI)	aORa (95% CI)	OR (95% CI)	aORa (95% CI)
Age (y)
<26	1.69 (1.13–2.52)	2.02 (1.31–3.12)	2.36 (1.43–3.89)	2.23 (1.25–3.99)
26–30	1.67 (1.16–2.39)	1.56 (1.09–2.22)	2.06 (1.28–3.30)	1.90 (1.18–3.06)
31–33	2.14 (1.38–3.29)	1.58 (1.06–2.35)	2.40 (1.36–4.25)	2.18 (1.32–3.62)
34–38	1.0	1.0	1.0	1.0
Study site
North	1.0	1.0	1.0	1.0
Northeast	0.85 (.56–1.29)	0.94 (.61–1.45)	0.80 (.47–1.37)	0.91 (.53–1.58)
South	1.20 (.83–1.72)	1.08 (.75–1.57)	1.14 (.73–1.77)	1.05 (.67–1.67)
Central	2.15 (1.47–3.14)	2.21 (1.52–3.21)	2.04 (1.29–3.23)	2.23 (1.41–3.53)
Contraceptive use
NHC	1.0	1.0	1.0	1.0
DMPA	0.92 (.64–1.33)	.90 (.63–1.31)	.88 (.56–1.38)	.87 (.55–1.35)
COC	1.42 (1.05–1.92)	1.27 (.93–1.74)	1.35 (.92–1.99)	1.22 (.81–1.83)
No. of lifetime partners
1	1.0	1.0	1.0	1.0
2	1.54 (1.08–2.20)	1.48 (1.04–2.11)	1.35 (.84–2.18)	1.26 (.78–2.04)
3	3.26 (1.99–5.34)	3.21 (1.99–5.17)	3.23 (1.85–5.64)	3.23 (1.89–5.50)
≥4	2.77 (1.82–4.23)	2.23 (1.47–3.39)	2.61 (1.53–4.45)	2.03 (1.18–3.50)
No. of partners L6M
1	1.0	1.0	1.0	1.0
>1	3.60 (1.34–9.71)	1.41 (.33–6.05)	4.98 (1.86–13.3)	1.78 (.32–10.01)
New partner L12M
No	1.0	1.0	1.0	1.0
Yes	3.31 (1.42–7.70)	2.44 (.71–8.45)	4.25 (1.84–9.78)	2.62 (.64–10.6)
Cervical ectopy
No	1.0	1.0	1.0	1.0
Yes	1.13 (.85–1.50)	1.09 (.79–1.49)	1.11 (.78–1.57)	1.06 (.71–1.57)
Bacterial vaginosis
No	1.0	1.0	1.0	1.0
Yes	2.56 (1.59–4.14)	2.85 (1.74–4.67)	3.07 (1.74–5.41)	3.45 (1.96–6.08)

Abbreviations: aOR, adjusted odds ratio; CI, confidence interval; COC, combined oral contraception; DMPA, depomedroxyprogesterone acetate; HPV, human papillomavirus; HR-HPV, HPV types considered to be high risk; L6M, last 6 months; L12M, last 12 months; NHC, nonhormonal contraception; OR, odds ratio.

^aAll variables mutually adjusted for.